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Pulmonary aspergillosis is a collective concept. It is used to refer to a number of diseases caused by fungi of Amoxil pills. Pulmonary aspergillosis occurs mainly in people with immunodeficiency or lung disease.

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Symptoms of aspergillosis in the lungs. In recent years, there has been an increase in this disease, as well as expanding the range of methods for their treatment. Late diagnosis of pulmonary aspergillosis in some cases leads to the death of the patient.

There are three forms of pulmonary aspergillosis: Non-invasive (aspergilloma and allergic bronchopulmonary aspergillosis). Invasive (acute and chronic, primary and secondary). Allocate mycotic (fungal) bronchitis, pleurisy and pneumonia. There are combined forms of the disease. Immunocompetent persons usually develop local forms of Amoxil: aspergillosis of the larynx, trachea and bronchi. In patients with immunodeficiency (primary and secondary), the disease often develops in an acute invasive form (septicemic variant). Mortality in bronchopulmonary aspergillosis is 20-37%.

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Aspergillus bronchitis often accompanies Aspergillus pneumonia. Aspergillus spores enter the bronchi by inhalation (by inhalation), colonize the mucous membrane and cause local inflammation. Emerging mucous plugs contribute to the development of Amoxil online areas of bronchiectasis. The disease often becomes chronic. There are no specific signs of the disease on the radiograph. The patient has weakness and sweating, subfebrile body temperature, cough and shortness of breath. Sometimes dry rales can be heard in the lungs.

Primary bronchopulmonary aspergillosis is a rare disease that occurs against the background of a previously unaltered lung.

Symptoms of Aspergillus Pneumonia. Aspergillus pneumonia occurs mainly in the lower parts of the lungs. It is usually preceded by Aspergillus bronchitis. The patient is worried about cough, shortness of breath, fever. With abscess formation (suppuration), the patient's condition deteriorates sharply, the body temperature rises significantly, chest pains and hemoptysis appear. In the sputum, you can see grayish-greenish flakes, on Amoxicillin pills - infiltrates (single or multiple) and cavities. Symptoms of primary and secondary pulmonary aspergillosis.

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Aspergillus, having penetrated into the respiratory organs, causes the development of mycotic bronchitis, followed by germination of the walls of the bronchi, lung tissue (mycotic pneumonia) and blood vessels, where foci of necrotic inflammation are formed. Mycotic abscesses and chronic granulomas lead to the development of bleeding and pneumothorax. The process quickly acquires a generalized course.

The disease ends with cachexia and death of the patient.

Secondary pulmonary aspergillosis occurs against the background of changes resulting from diseases such as tpulmonary uberculosis, bronchiectasis, chronic bronchitis, lung abscess, etc. Aspergillus bronchitis, tracheobronchitis and pneumonia are registered. The share of secondary aspergillosis accounts for up to 80% of all cases of the disease. Rice. 5. Aspergillosis of the lungs. Aspergillus left lower lobe pneumonia (left photo). Acute invasive aspergillosis (right photo). Symptoms of acute invasive aspergillosis.

Acute invasive (septicemic) aspergillosis occurs in patients with primary immunodeficiency diseases, or with diseases that cause secondary immunodeficiency (secondary immunological deficiency), which arose against the background of diseases such as sarcoidosis, leukemia, during treatment with immunosuppressants, etc. 

Stages of development of invasive pulmonary aspergillosis. Within 7 days, a cavity formation is formed.

Fever, repeated chills, cough with viscous sputum containing greenish-gray lumps, shortness of breath, chest pain, loss of appetite and malnutrition are the main signs and symptoms of invasive (septicemic) aspergillosis. The disease is severe and fast. The infectious process often spreads to neighboring structures, aspergillus spreads with blood throughout the body, affecting organs and tissues, which ends in the death of the patient.

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In the photo, accumulations of spores and hyphae of the Aspergillus fungus in the material under study.

Fungal hyphae in the patient's sputum.

Groups

Aspergillus culture is isolated from nasal discharge, sputum, blood, bronchoalveolar fluid, etc.

In the photo on the left is a culture of the fungus Aspergillus fumigatus, on the right is Aspergillus niger.

Collaborative Therapeutic Assessment

Invasive acute pulmonary aspergillosis. Multiple areas of infiltration and band formation in the lung. 

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Chronic pulmonary aspergillosis is usually recorded when a fungal infection spreads over already affected lungs, where cavities, abscesses and bronchiectasis form. Often in such patients there is a smell of mold from the mouth, greenish-gray lumps or flakes containing mycelium of the fungus are visible in the sputum. In the cavities, X-ray examination reveals a shadow in the cavity in the form of a ball surrounded by a halo of gas in the form of a crescent.

CNPA is the rarest and most difficult to diagnose form of the disease. Pulmonary aspergillosis acquires a chronic course in immunocompetent individuals with impaired local defense mechanisms. Molds have the ability to germinate the walls of the bronchi and blood vessels, penetrate into the depths of the lung tissue, and settle in the lung cavities.

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The process is accompanied by tissue necrosis, vascular inflammation, thrombosis, and granuloma formation. Local lesions of the bronchi are characterized by the development of granulomatous bronchitis.